铁调素(Hepc)重组蛋白

Recombinant Hepcidin (Hepc)

HAMP; HFE2B; PLTR; LEAP1; Hepcidin Antimicrobial Peptide; Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor

  • 铁调素(Hepc)重组蛋白 产品包装(模拟)
  • 铁调素(Hepc)重组蛋白 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

序列

用法

PBS或其它。

储存

避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保?#21183;?#20869;,在?#23454;?#30340;条件下存储,损失?#23454;?#20110;5%。

相关产品

编号 适用物种:Pan-species (General,通用) 应用(仅供研究使用,不用于临床诊断!)
RPB979Ge01 铁调素(Hepc)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.

参考文献

杂志 参考文献
World J Gastroenterol. Hepcidin expression in colon during trinitrobenzene sulfonic acid-induced colitis in rats [Pubmed: 24764672]
International Journal of Advanced Research Modulations of serum hepcidin, IL6 and iron status by different exercise regimens in ovarectomized rats [Com:Source]
Neurochemical Journal Serum iron metabolism markers including hepcidin in multiple sclerosis patients [Springer:Source]
Afro-Egypt J Infect Endem Dis Monitoring Hepcidin Level in Chronic Hepatitis C Virus Patients during Therapy [Zu:Source]
Gastroenterology Gluconeogenic signals regulate iron homeostasis via hepcidin in mice [Pubmed:Pmc3989026]
J Card Fail. Inappropriate expression of hepcidin by liver congestion contributes to anemia and relative iron deficiency [Pubmed:24440572]
Food Funct. The action of JAK, SMAD and ERK signal pathways on hepcidin suppression by polysaccharides from Angelica sinensis in rats with iron deficiency anemia [Pubmed:24752529]
Free Radic Res. Changes in skeletal muscle iron metabolism outpace amyotrophic lateral sclerosis onset in transgenic rats bearing the G93A hmSOD1 gene mutation [Pubmed:25175826]
Saudi J Kidney Dis Transpl. Hepcidin and regulation of iron homeostasis in maintenance hemodialysis patients [Pubmed:25193892]
J Endocrinol Invest.? The interplay among iron metabolism, endothelium and inflammatory cascade in dysmetabolic disorders [Pubmed:25245337]
Gastroenterology Research and Practice An Evaluation of the Correlation between Hepcidin Serum Levels and Disease Activity in Inflammatory Bowel Disease [Pubmed:25628652]
Clin Lab. Serum hepcidin levels in Bulgarian population. [Pubmed:25651734]
The Tohoku Journal of Experimental Medicine Liver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia [Pubmed:25742771]
Cancer Res Hepcidin regulation in prostate and its disruption in prostate cancer [PubMed: 25858146]
Biochem Biophys Res Commun B-cell translocation gene 2 promotes hepatic hepcidin production via induction of Yin Yang 1 [PubMed: 25839654]
Blood Purif Effect of a More Permeable Dialysis Membrane on ESA Resistance in Hemodialysis Patients - A Pilot Investigation [PubMed: 26536083]
Asian Journal of Clinical Nutrition Urinary Hepcidin in Diagnosis of Iron Deficiency Anemia [Openview: E01Ad7C4A9109Ed5Fadb03Ec206D7Bdc]
Front Psychol Ferrous sulfate, but not iron polymaltose complex, aggravates local and systemic inflammation and oxidative stress in dextran sodium sulfate-induced colitis in rats [PubMed: 25852597]
Biol Trace Elem Res Iron Supplementation Attenuates the Inflammatory Status of Anemic Piglets by Regulating Hepcidin [PubMed: 25774043]
APS Journals Kupffer cell depletion protects against the steatosis, but not the liver damage, induced by marginal copper, high fructose diet in male rats. [PubMed: 25813056]
European Journal of Haematology Hepcidin in tumor‐related iron deficiency anemia and tumor‐related anemia of chronic disease: pathogenic mechanisms and diagnosis [PubMed: 24954786]
WJA The Effects of Treatment on Serum Hepcidin and Iron Homeostasis in HIV-1-Infected In-dividuals [Journal: 59107]
Nutrition, Metabolism and Cardiovascular Diseases Hepcidin?and?iron?metabolism?associated?with?cardiometabolic?risk factors?in?children: A case-control?study. [Pubmed:27139516]
Food Funct The effects of polysaccharides from the root of Angelica sinensis on tumor growth and iron metabolism in H22-bearing mice [Pubmed:26757699]
Antioxid Redox Signal. Hydrogen sulfide attenuates inflammatory hepcidin by reducing IL-6 secretion and promoting SIRT1-mediated STAT3 deacetylation [Pubmed:26154696]
BioMed Research International The Impact of Acute Matriptase Inhibition in Hepatic Inflammatory Models. [pubmed:27642598]
Frontiers in Neuroscience In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution. [pubmed:27729845]
Experimental Biology and Medicine Effects of iron supplementation in mice with hypoferremia induced by obesity [pubmed:27439539]
Nutrition, Metabolism and Cardiovascular Diseases Hepcidin and iron metabolism associated with cardiometabolic risk factors in children: A case–control study [pubmed:27139516]
PLOS?ONE S-Propargyl-Cysteine, a?Novel?Hydrogen?Sulfide?Donor,?Inhibits?Inflammatory?Hepcidin?and Relieves Anemia of Inflammation by Inhibiting IL-6/STAT3 Pathway. [pubmed:27649298]
Endocrine connections Hepcidin links gluco-toxicity to pancreatic beta cell dysfunction by inhibiting Pdx-1 expression [pubmed:28179377]
Maternal and cord blood hepcidin levels based on gestational weeks in term and preterm infants [publication:305921433_Maternal_and_cord_blood_hepc]
Oxidative Medicine and Cellular Longevity Acidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation [pubmed:29147463]
The Royal Society of Chemistry Silkworm feces extract improves iron deficiency anemia via suppressing hepcidin expression and promoting iron-regulatory proteins expression [DOI: 10.1039/C7RA09576G]
Journal of Inflammation Evaluation of a competitive hepcidin ELISA assay in the differential diagnosis of iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients [10.1186:s12950-017-0166-3]
Antioxidants and Redox Signaling AMPK serves as a Therapeutic Target against Anemia of Inflammation [pubmed:27923278]
NutriciónHospitalaria Micronutrient supplementation in gastric bypass surgery: prospective study on in??? ammation and iron metabolism in premenopausal women [10.20960/nh.1162]
The Japanese Society of Hematology Hepcidin suppression in β?thalassemia is associated with the down?regulation of atonal homolog 8 [pubmed:28405918]
Tuberculosis Modulation of iron status biomarkers in tuberculosis-diabetes co-morbidity [10.1016/j.tube.2017.11.011]
Oman Medical Journal The Role of Insulin Therapy in Correcting Hepcidin Levels in Patients with Type 2 Diabetes Mellitus. [pubmed:28584599]
Cellular?Physiology and Biochemistry The Effects of Angelica Sinensis Polysaccharide on Tumor Growth and Iron Metabolism by Regulating Hepcidin in Tumor-Bearing Mice [Pubmed:29843136]
Cellular?Microbiology? inhibits ferroportin translation by modulating FBXL5‐IRP2 axis for its growth within host macrophages [Pubmed:29470856]
Journal of Histochemistry & Cytochemistry Acute and Chronic Iron Overloading Differentially Modulates the Expression of Cellular Iron-homeostatic Molecules in Normal Rat Kidney [Pubmed:29873589]
Clinical and Experimental?Medicine Increased NGAL level associated with iron store in chronic kidney disease with anemia [Pubmed:29909502]
Hematology Relationship between obesity and iron deficiency anemia: is there a role of hepcidin? [Pubmed:29318945]
Hepcidin serum levels in HCV chronically mono-infected na?ve patients, compared to healthy individuals [77856]
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